I have fished Biloxi a few times , never was a meat haul. Backtrack to the Louisiana Delta area and the fishing will be much better, IMHO.
Either location will be HOTT.
Offshore in Mississippi is a long ride, We went 50 miles miles to fish oil rigs one year , caught some huge snapper but season was closed.
Got in to huge schools of redfish on surface one year , federal waters , No keeping redfish.
If you want to fish the Shell Beach , La area give this man a call
http://www.saltydogchartersllc.com/ MO