If you're looking for a "mother ship" trip I recommend DMJ Charters
https://www.facebook.com/DMJCharters/ Most have the same setups, the same skiffs, go to the same place so what you're really shopping for is a Captain and crew.
I've been going on trips to Chandelier for almost 20 years, I've always gone out with SouthernSportsFishing. The first boat we went out on was the V, back when they ran two big boats- a few years before Katrina. We then booked on the VI and after Katrina they sold the V and only ran one boat with various Captains over the years. They had the best boat, the best skiffs and with Dennis the best overall experience although I'm working off of stories told about the other boats...they stay pretty booked up too so perhaps I'm wrong.
Cap't Dennis Marshall was BY FAR the very best Captain that we ever ran with, he ran the VI for many years. He and his crews always worked very well together as a team for us...that is not always the case. We've seen everything from a Cap't who is only there to drive the boat to guys who don't put much effort in to stuff I wont mention to outstanding teamwork taking good care of us.
Dennis retired from the fire department and bought his own boat last year and he's pretty booked up- for a brand new operation that speaks volumes.
I haven't been out with anything other than those two but I'll promise you that you will be very hard pressed to find a better operation. He has two guys crewing the boat with him, one is a licensed captain and the other is a lifetime MS coast resident and experienced fisherman around the islands. They will go out and show you where/what/how if you need them to, that isn't always the case.
We just got back from a trip with them after laying off for two years. I had a significant accident four years ago, was run over by my own skiff, cut both arteries in my left arm and probably shouldn't be typing this right now; clearly my job here isn't finished. I went back on the same boat almost exactly a year after the accident and if Dennis hadn't had bought "Backdraft" and started running out there I wouldn't have ever gone back, after this trip we are already booked for next year.
We've always gone in April or October but Christian, the crewmember who's been out there all his life told me his two favorite months are May and November. Said April weather is too unpredictable and same for October. Our experience kind of makes this ring true- this last trip was right in between a big storm and there was another right behind us. Definitely affected fishing and with the advanced planning that is required and all of the anticipation it's probably smart to book when weather is a bit more predictable. (we still caught a ton)
One thing was different this year- there were a lot more fisherman than I remember. There were at least 5 big boats out there with 8-10 skiffs running out of each one. I can remember trips seeing only a couple, maybe three plus the Pelican barge that has occasional visitors. There's even a dadgum oil platform that someone hauled out there on stilts with skiffs up top planted RIGHT in the middle of the catch-em-all bar channel, I guess for fisherman to rent, I don't know.
I cannot guarantee fish but I can guarantee that you'll be well taken care of and will have a great time with Dennis and his crew.