Premixed Trufuel in Outboard motors?

Has anyone used the TruFuel premixed gas in 2 cylce outboards? I have a small 2.5hp motor I would like to try in. It would save a lot of hassle from pre-mixing. Their website shows a product for 4 cycle and talks about using in air cooled 2 cycle motors. What would keep me from trying it in a 2 cycle water cooled motor?

I wouldn’t run it in a big motor but for that little guy should be fine.

I run that stuff in all my yard tools. Been one year of not messing with any spark plugs or anything.... Great stuff. Only problem is that its 8$ a gallon.