Braid + Fluoro leader.
I use braid + leader because it's easier to manage for me. I backlash a lot with all fluoro unless spending big$ on premium line, plus there is greater sensitivity with braid.
To overcome the problem of braid digging in on itself, I use 50 lb. Anything lighter has too small of diameter and it digs a lot.
The braid>>fluoro knot I use is the Alberto Knot
You can only use this knot on rods with semi-micro or regular sized guides. The FG knot is thinner but I have difficulty tying it, especially out on the water.
4 other advantages are:
1. Braid lasts a lot longer. No worries about oxidation, sunlight, kinks, etc.
2. You minimize the expense of fluoro bc you're only using ~3-4 feet at a time for leader.
3. You can use a high visibility color and still get bit.
4. You can use a stronger fluoro leader than you otherwise would have had as your main line had you chosen to go 100% fluoro which means fewer break-offs.
The downside are wind knots. I get those occassionally, but have learned to manage with them pretty well.