Great town. Lived there for several years. PM me if you want ideas on places to eat, etc.
Jocassee is a little over an hour from Greenville and by far the most beautiful lake in the area. Healthy trout population, too. Very deep with little structure. Keowee is below Jocassee and very nice as well. Hartwell is probably the best bass lake in the chain, but the least scenic so it just depends on what you're looking for.