I sometimes fly fish from my kayak, and yes, it is definitely more challenging to cast. If I'm on the river, I will stop and get out to cast in most situations. On the lakes I usually cast from the yak. It really helps to get the yak oriented in the right direction so you don't have to contort your body too much. also watch for rods that you may have sticking up behind you in a rod holder. I don't stand up in my yak, but if you could that would help immensely.